Pub. Date : 2016 Mar
PMID : 26348251
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Additionally, alginate-encapsulated transgenic designer cells remained responsive to the release of the pro-inflammatory cytokine tumor necrosis factor (TNF) from the whole-blood culture upon exposure to bacterial lipopolysaccharide (LPS). | Alginates | tumor necrosis factor | Homo sapiens |
| 2 | Additionally, alginate-encapsulated transgenic designer cells remained responsive to the release of the pro-inflammatory cytokine tumor necrosis factor (TNF) from the whole-blood culture upon exposure to bacterial lipopolysaccharide (LPS). | Alginates | tumor necrosis factor | Homo sapiens |
| 3 | TNF diffused into the alginate capsules, bound to the specific TNF receptors on the transgenic designer cells" surface and triggered the expression of the reporter gene SEAP (human placental secreted alkaline phosphatase) that was rewired to the TNF-specific signaling cascade. | Alginates | tumor necrosis factor | Homo sapiens |