Pub. Date : 2015 Nov 1
PMID : 26344854
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | UDP-galactose 4-epimerase (GalE) catalyzes the interconversion of UDP-glucose (UDP-Glc) and UDP-galactose (UDP-Gal), which is a pivotal step in the Leloir pathway for d-galactose metabolism. | Galactose | UDP-galactose-4-epimerase | Homo sapiens |
2 | Our data showed that TM0509 is a UDP-galactosugar 4-epimerase involved in d-galactose metabolism; consequently, this study provides the first detailed characterization of a hyperthermophilic GalE. | Galactose | UDP-galactose-4-epimerase | Homo sapiens |
3 | Moreover, the promiscuous substrate specificity of TMGalE, which is more similar to human GalE than E. coli GalE, supports the notion that TMGalE might exhibit the earliest form of sugar-epimerizing enzymes in the evolution of galactose metabolism. | Galactose | UDP-galactose-4-epimerase | Homo sapiens |
4 | Moreover, the promiscuous substrate specificity of TMGalE, which is more similar to human GalE than E. coli GalE, supports the notion that TMGalE might exhibit the earliest form of sugar-epimerizing enzymes in the evolution of galactose metabolism. | Galactose | UDP-galactose-4-epimerase | Homo sapiens |