Pub. Date : 2015 Nov
PMID : 26331698
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | L-ASNase treatment and Gln deprivation dramatically disrupted the refilling of the tricarboxylic acid (TCA) cycle by intracellular glutamate (Glu) and disturbed the mitochondrial integrity, which were alleviated by various anaplerotic TCA cycle intermediates, suggesting a direct contribution of glutaminase activity of L-ASNase. | Glutamic Acid | asparaginase and isoaspartyl peptidase 1 | Homo sapiens |
| 2 | L-ASNase treatment and Gln deprivation dramatically disrupted the refilling of the tricarboxylic acid (TCA) cycle by intracellular glutamate (Glu) and disturbed the mitochondrial integrity, which were alleviated by various anaplerotic TCA cycle intermediates, suggesting a direct contribution of glutaminase activity of L-ASNase. | Glutamic Acid | asparaginase and isoaspartyl peptidase 1 | Homo sapiens |