Title : In Vitro Characterization of the Human Liver Microsomal Kinetics and Reaction Phenotyping of Olanzapine Metabolism.

Pub. Date : 2015 Nov

PMID : 26329789






1 Functional Relationships(s)
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1 Consistent with previous reports, UGT1A4, CYP1A2, and flavin-containing monooxygenase 3 play major roles in catalyzing the formation of OLZ-10-N-glucuronide, 7-hydroxy-OLZ, and OLZ-N-oxide, respectively. 7-hydroxy-olz flavin containing dimethylaniline monoxygenase 3 Homo sapiens