Title : Pharmacological evidence for the mediation of the panicolytic effect of fluoxetine by dorsal periaqueductal gray matter μ-opioid receptors.

Pub. Date : 2015 Dec

PMID : 26320545






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Previously reported results have shown that the inhibitory effect of fluoxetine on escape behavior, interpreted as a panicolytic-like effect, is blocked by pretreatment with either the opioid receptor antagonist naloxone or the 5-HT1A receptor (5-HT1A-R) antagonist WAY100635 via injection into the dorsal periaqueductal gray matter (dPAG). dpag 5-hydroxytryptamine receptor 1A Homo sapiens
2 Previously reported results have shown that the inhibitory effect of fluoxetine on escape behavior, interpreted as a panicolytic-like effect, is blocked by pretreatment with either the opioid receptor antagonist naloxone or the 5-HT1A receptor (5-HT1A-R) antagonist WAY100635 via injection into the dorsal periaqueductal gray matter (dPAG). dpag 5-hydroxytryptamine receptor 1A Homo sapiens
3 Additionally, reported evidence indicates that the mu-opioid receptor (MOR) interacts with the 5-HT1A-R in the dPAG. dpag 5-hydroxytryptamine receptor 1A Homo sapiens