Pub. Date : 2015 Dec
PMID : 26320545
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Additionally, reported evidence indicates that the mu-opioid receptor (MOR) interacts with the 5-HT1A-R in the dPAG. | dpag | opioid receptor mu 1 | Homo sapiens |
| 2 | Additionally, reported evidence indicates that the mu-opioid receptor (MOR) interacts with the 5-HT1A-R in the dPAG. | dpag | opioid receptor mu 1 | Homo sapiens |
| 3 | In the present work, pretreatment of the dPAG with the selective MOR blocker CTOP antagonized the anti-escape effect of chronic fluoxetine (10 mg/kg, i.p., daily, for 21 days), as measured in the elevated T-maze (ETM) test, indicating mediation of this effect by the MOR. | dpag | opioid receptor mu 1 | Homo sapiens |
| 4 | In the present work, pretreatment of the dPAG with the selective MOR blocker CTOP antagonized the anti-escape effect of chronic fluoxetine (10 mg/kg, i.p., daily, for 21 days), as measured in the elevated T-maze (ETM) test, indicating mediation of this effect by the MOR. | dpag | opioid receptor mu 1 | Homo sapiens |
| 5 | In addition, the combined administration of sub-effective doses of the selective MOR agonist DAMGO (intra-dPAG) and sub-effective doses of chronic as well as subchronic (7 days) fluoxetine increased avoidance and escape latencies, suggesting that the activation of MORs may facilitate and accelerate the effects of fluoxetine. | dpag | opioid receptor mu 1 | Homo sapiens |