Title : Pyrroloquinoline Quinone Decelerates Rheumatoid Arthritis Progression by Inhibiting Inflammatory Responses and Joint Destruction via Modulating NF-κB and MAPK Pathways.

Pub. Date : 2016 Feb

PMID : 26319019






1 Functional Relationships(s)
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1 Our observations showed that pretreatment with PQQ significantly inhibited the expression of matrix metalloproteinase (MMP)-1 and MMP-3 and suppressed the production of proinflammatory mediators such as TNF-alpha and IL-6 in IL-1beta-treated SW982 cells. PQQ Cofactor matrix metallopeptidase 1 Homo sapiens