Pub. Date : 2015 Oct
PMID : 26314369
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Zn(II)-curc targets p53 in thyroid cancer cells. | Zinc | tumor protein p53 | Homo sapiens |
| 2 | Here, we investigated whether Zn(II)-curc could affect p53 in thyroid cancer cells with both p53 mutation (R273H) and wild-type p53. | Zinc | tumor protein p53 | Homo sapiens |
| 3 | In addition, Zn(II)-curc triggered p53 target gene expression in wild-type p53-carrying cells. | Zinc | tumor protein p53 | Homo sapiens |
| 4 | In addition, Zn(II)-curc triggered p53 target gene expression in wild-type p53-carrying cells. | Zinc | tumor protein p53 | Homo sapiens |
| 5 | Taken together, our data indicate that Zn(II)-curc promotes the reactivation of p53 in thyroid cancer cells, providing in vitro evidence for a potential therapeutic approach in thyroid cancers. | Zinc | tumor protein p53 | Homo sapiens |