Title : Effects of 22 Novel CYP2D6 Variants Found in the Chinese Population on the Bufuralol and Dextromethorphan Metabolisms In Vitro.

Pub. Date : 2016 Mar

PMID : 26310775






2 Functional Relationships(s)
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1 Effects of 22 Novel CYP2D6 Variants Found in the Chinese Population on the Bufuralol and Dextromethorphan Metabolisms In Vitro. Dextromethorphan cytochrome P450 family 2 subfamily D member 6 Homo sapiens
2 The remaining 22 variants exhibited significantly decreased intrinsic clearance values for bufuralol 1"-hydroxylation and 20 variants showed significantly lower intrinsic clearance values for dextromethorphan O-demethylation than those of the wild-type CYP2D6.1. Dextromethorphan cytochrome P450 family 2 subfamily D member 6 Homo sapiens