Pub. Date : 2016 Mar
PMID : 26310775
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Effects of 22 Novel CYP2D6 Variants Found in the Chinese Population on the Bufuralol and Dextromethorphan Metabolisms In Vitro. | Dextromethorphan | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |
2 | The remaining 22 variants exhibited significantly decreased intrinsic clearance values for bufuralol 1"-hydroxylation and 20 variants showed significantly lower intrinsic clearance values for dextromethorphan O-demethylation than those of the wild-type CYP2D6.1. | Dextromethorphan | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |