Title : Selective inactivation of NADPH oxidase 2 causes regression of vascularization and the size and stability of atherosclerotic plaques.

Pub. Date : 2015 Oct

PMID : 26298737






1 Functional Relationships(s)
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1 RESULTS: Nox2ds-tat inhibited Nox-derived superoxide determined by cytochrome C in carotid arteries (2.3 +- 0.1 vs 1.7 +- 0.1 O2( -) nmol/min*mg protein; P < 0.01) and caused a significant regression in atherosclerotic plaques in aorta (66 +- 6 mum(2) vs 37 +- 1 mum(2); scrmb vs. Nox2ds-tat; P < 0.001). Superoxides cytochrome b-245, beta polypeptide Mus musculus