Title : Phenotypic Screening for Friedreich Ataxia Using Random shRNA Selection.

Pub. Date : 2015 Oct

PMID : 26286937






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Frataxin chaperones iron in the mitochondrial matrix and regulates the iron-sulfur cluster (ISC) assembly complex. Iron frataxin Homo sapiens
2 Frataxin chaperones iron in the mitochondrial matrix and regulates the iron-sulfur cluster (ISC) assembly complex. Iron frataxin Homo sapiens
3 Decreased expression of frataxin is associated with decreased ISC assembly, mitochondrial iron accumulation, and increased oxidative stress, all of which contribute to mitochondrial dysfunction. Iron frataxin Homo sapiens