Title : Apolipoprotein A-I inhibits experimental colitis and colitis-propelled carcinogenesis.

Pub. Date : 2016 May 12

PMID : 26279300






2 Functional Relationships(s)
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1 We show that ApoA-I is expressed at higher levels in the proximal compared with the distal part of the colon and its ablation in mice results in exaggerated DSS-induced colitis and disruption of epithelial architecture in larger areas of the large intestine. dss apolipoprotein A-I Mus musculus
2 Genetic interference with ApoA-I levels in vivo impacted on the number, size and distribution of AOM/DSS-induced colon tumors. dss apolipoprotein A-I Mus musculus