Title : IFNγ+ Treg in-vivo and in-vitro represent both activated nTreg and peripherally induced aTreg and remain phenotypically stable in-vitro after removal of the stimulus.

Pub. Date : 2015 Aug 13

PMID : 26268522






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 CD4+CD25+ enriched PBL stimulated with PMA/Ionomycin in the presence of rIFNgamma were rather resistant to the effect of rIFNgamma, in contrast to CD4+CD25- enriched PBL which showed increasing total Treg with Helios+ Treg switching from IFNgamma- to IFNgamma+ and increasing Helios-IFNgamma+ Treg. Tetradecanoylphorbol Acetate interferon gamma Rattus norvegicus