Title : Adaptive aneuploidy protects against thiol peroxidase deficiency by increasing respiration via key mitochondrial proteins.

Pub. Date : 2015 Aug 25

PMID : 26261310






1 Functional Relationships(s)
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1 Thus, thiol peroxidase deficiency requires dosage compensation of CCP1 and UTH1 via chromosome XI aneuploidy, wherein these proteins support hydroperoxide removal with the reducing equivalents generated by the electron transport chain. Hydrogen Peroxide cytochrome-c peroxidase Saccharomyces cerevisiae S288C