Title : Regulation of ADAM10 and ADAM17 by Sorafenib Inhibits Epithelial-to-Mesenchymal Transition in Epstein-Barr Virus-Infected Retinal Pigment Epithelial Cells.

Pub. Date : 2015 Aug

PMID : 26244291






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Sorafenib significantly inhibited production of TGF-beta1, VEGF, IL-6, IL-8, MCP-1, and TNF-alpha and blocked the activation of migration-related signaling molecules, such as HIF-1alpha, p-STAT3, MMP2, and Ang-1. Sorafenib C-X-C motif chemokine ligand 8 Homo sapiens