Title : Label-free LC-MS analysis of HER2+ breast cancer cell line response to HER2 inhibitor treatment.

Pub. Date : 2015 Aug 4

PMID : 26238995






1 Functional Relationships(s)
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1 RESULTS: Following 12 ours treatment with different HER2-inhibitors in the BT474 cell-line; compared to the untreated cells, 16 proteins changed significantly in abundance following lapatinib treatment (1 muM), 21 proteins changed significantly following neratinib treatment (150 nM) and 38 proteins changed significantly following afatinib treatment (150 nM). Lapatinib latexin Homo sapiens