Title : Dose-Dependent Bidirectional Effect of Angiotensin IV on Abdominal Aortic Aneurysm via Variable Angiotensin Receptor Stimulation.

Pub. Date : 2015 Sep

PMID : 26238445






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The beneficial effect of medium-dose Ang IV may be contributed to the stimulation of type 4 angiotensin receptor (AT4R) and AT2R with suppression of AT1R, activation of Akt, and inhibition of nuclear factor-kappaB, as these beneficial effects were largely reversed by cotreatment with the AT4R antagonist divalinal-Ang IV in Ang II-infused mice or with the Akt inhibitor A6730 in Ang II-stimulated human smooth muscle cells. divalinal angiogenin, ribonuclease, RNase A family, 5 Mus musculus