Pub. Date : 1989 Dec
PMID : 2623648
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Early postimplantation embryolethality in mice following in utero inhibition of adenosine deaminase with 2"-deoxycoformycin. | Pentostatin | adenosine deaminase | Mus musculus |
| 2 | In the present study, we examined the effects of intrauterine exposure to 2"-deoxycoformycin (dCF; pentostatin), a potent irreversible inhibitor of ADA, on early postimplantation development. | Pentostatin | adenosine deaminase | Mus musculus |
| 3 | In the present study, we examined the effects of intrauterine exposure to 2"-deoxycoformycin (dCF; pentostatin), a potent irreversible inhibitor of ADA, on early postimplantation development. | Pentostatin | adenosine deaminase | Mus musculus |
| 4 | Treatment of pregnant dams with dCF on day 7 produced a complete (greater than 99%) inhibition of ADA activity in the antimesometrial decidua by 30 min, induced excessive cell death in the prospective neural plate and primary mesenchyme of the trilaminar disc by 6 h, and arrested embryonic development at an early somite stage. | Pentostatin | adenosine deaminase | Mus musculus |