Title : Substance P enhances microglial density in the substantia nigra through neurokinin-1 receptor/NADPH oxidase-mediated chemotaxis in mice.

Pub. Date : 2015 Oct 1

PMID : 26223840






1 Functional Relationships(s)
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1 Mechanistic studies revealed that both the SP receptor neurokinin-1 receptor (NK1R) and the superoxide-producing enzyme NADPH oxidase (NOX2) were necessary for SP-mediated chemotaxis in microglia. Superoxides cytochrome b-245, beta polypeptide Mus musculus