Pub. Date : 2015 Aug 18
PMID : 26223367
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Flexible Linker Modulates Glycosaminoglycan Affinity of Decorin Binding Protein A. Decorin binding protein A (DBPA) is a glycosaminoglycan (GAG)-binding adhesin found on the surface of the bacterium Borrelia burgdorferi (B. burgdorferi), the causative agent of Lyme disease. | Glycosaminoglycans | Y-box binding protein 3 | Homo sapiens |
| 2 | Flexible Linker Modulates Glycosaminoglycan Affinity of Decorin Binding Protein A. Decorin binding protein A (DBPA) is a glycosaminoglycan (GAG)-binding adhesin found on the surface of the bacterium Borrelia burgdorferi (B. burgdorferi), the causative agent of Lyme disease. | Glycosaminoglycans | Y-box binding protein 3 | Homo sapiens |
| 3 | Interestingly, DBPA from different strains (B31, N40, and PBr) show significant differences in GAG affinities, but the structural basis for the differences is not clear. | Glycosaminoglycans | Y-box binding protein 3 | Homo sapiens |
| 4 | In this study, we show that GAG affinity of N40 DBPA is modulated in part by flexible segments that control access to the GAG binding site, such that shortening of the linker leads to higher GAG affinity when analyzed using ELISA, gel mobility shift assay, solution NMR, and isothermal titration calorimetry. | Glycosaminoglycans | Y-box binding protein 3 | Homo sapiens |
| 5 | In this study, we show that GAG affinity of N40 DBPA is modulated in part by flexible segments that control access to the GAG binding site, such that shortening of the linker leads to higher GAG affinity when analyzed using ELISA, gel mobility shift assay, solution NMR, and isothermal titration calorimetry. | Glycosaminoglycans | Y-box binding protein 3 | Homo sapiens |
| 6 | In this study, we show that GAG affinity of N40 DBPA is modulated in part by flexible segments that control access to the GAG binding site, such that shortening of the linker leads to higher GAG affinity when analyzed using ELISA, gel mobility shift assay, solution NMR, and isothermal titration calorimetry. | Glycosaminoglycans | Y-box binding protein 3 | Homo sapiens |