Title : Predictive value of STMN1 gene promoter polymorphism (-2166T>C) in patients with advanced NSCLC treated with the combination of platinum compounds and vinorelbine.

Pub. Date : 2015 Sep

PMID : 26220844






3 Functional Relationships(s)
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Protein Name
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1 Predictive value of STMN1 gene promoter polymorphism (-2166T>C) in patients with advanced NSCLC treated with the combination of platinum compounds and vinorelbine. Vinorelbine stathmin 1 Homo sapiens
2 The aim of the study was to determine the relationship between a single nucleotide polymorphism (SNP) of the promoter of STMN1 gene -2166T>C) and the effectiveness of chemotherapy based on platinum compounds and vinorelbine in patients with NSCLC. Vinorelbine stathmin 1 Homo sapiens
3 CONCLUSION: Rare TT genotype of STMN1 gene may be an unfavorable predictive factor of chemotherapy based on platinum compounds and vinorelbine, in patients with NSCLC. Vinorelbine stathmin 1 Homo sapiens