Title : Glucagon-like peptide-2-loaded microspheres as treatment for ulcerative colitis in the murine model.

Pub. Date : 2015

PMID : 26218715






1 Functional Relationships(s)
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1 pGLP-2 microspheres showed 20.36% in initial burst and constant release for at least 9 d. In the DSS-treated mice, a single injection of GLP-2 microspheres significantly increased the body weight, colonic length, small intestinal weight and mRNA expression of Occludin, decreased the colonic damage score, mRNA expression of IL-6, IL-10, TNF-alpha and IFN-gamma. Dextran Sulfate interferon gamma Mus musculus