Title : Dexmedetomidine attenuates acute lung injury induced by lipopolysaccharide in mouse through inhibition of MAPK pathway.

Pub. Date : 2015 Oct

PMID : 26211495






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1 The results showed that pretreatment with Dex considerably reduced neutrophil infiltration and pulmonary edema, and significantly reduced protein concentrations in the BALF, as well as suppressed LPS-induced elevation of proinflammatory cytokines (TNF-alpha and IL-1beta) in the serum. Dexmedetomidine interleukin 1 beta Mus musculus