Title : Peroxisome proliferator activated receptor-γ agonists protect oligodendrocyte progenitors against tumor necrosis factor-alpha-induced damage: Effects on mitochondrial functions and differentiation.

Pub. Date : 2015 Sep

PMID : 26210873

1 Functional Relationships(s)
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Protein Name
1 We demonstrate that the inhibition of OL differentiation by TNF-alpha is associated with i) increased mitochondrial superoxide production; ii) decreased mitochondrial membrane potential (mMP); and iii) decreased ADP-induced Ca(2+) oscillations, which we previously showed to be dependent on efficient mitochondria. Superoxides tumor necrosis factor Homo sapiens