Title : Robust inhibitory effects of conjugated linolenic acids on a cyclooxygenase-related linoleate 10S-dioxygenase: Comparison with COX-1 and COX-2.

Pub. Date : 2015 Oct

PMID : 26209563






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Jacaric acid (8Z,10E,12Z-18:3) and its 12E isomer, 8Z,10E,12E-18:3, strongly inhibit the activity of COX-1 with a Ki of ~1.7 and ~1.1muM, respectively. jacaric acid mitochondrially encoded cytochrome c oxidase I Homo sapiens