Pub. Date : 2015
PMID : 26207907
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Simvastatin Increases Fibulin-2 Expression in Human Coronary Artery Smooth Muscle Cells via RhoA/Rho-Kinase Signaling Pathway Inhibition. | Simvastatin | fibulin 2 | Homo sapiens |
2 | Simvastatin induced a significant increase in mRNA and protein levels of fibulin-2 at 24 hours of incubation (p<0.05), but it did not affect fibulin-1, -4, and -5 expression. | Simvastatin | fibulin 2 | Homo sapiens |
3 | Simvastatin increased mRNA levels and protein expression of the ECM protein fibulin-2 through a RhoA and Rho-Kinase-mediated pathway. | Simvastatin | fibulin 2 | Homo sapiens |