Title : Variation in the inhibitory potency of terbinafine among genetic variants of CYP2D6.

Pub. Date : 2015 Aug

PMID : 26195224






1 Functional Relationships(s)
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1 In a competitive inhibition study, the metabolic activity of the CYP2D6 was assessed based on their demethylation of dextromethorphan in the presence or absence of TER, and the time-dependency of the inhibitory effects were examined by preincubating the enzymes with TER. Dextromethorphan cytochrome P450 family 2 subfamily D member 6 Homo sapiens