Title : Is Parkinson's disease a progressive siderosis of substantia nigra resulting in iron and melanin induced neurodegeneration?

Pub. Date : 1989

PMID : 2618593






1 Functional Relationships(s)
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1 Indeed H2O2 derived from MAO B reaction and autooxidation of dopamine to melanin in the SN can drive the iron dependent Fenton reaction. Iron monoamine oxidase B Homo sapiens