Title : Nicotine Induces Tumor Growth and Chemoresistance through Activation of the PI3K/Akt/mTOR Pathway in Bladder Cancer.

Pub. Date : 2015 Sep

PMID : 26184482






5 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Phospho-specific Akt (pAkt) and phospho-specific p70 S6 kinase (pS6) were significantly upregulated by nicotine exposure. Nicotine taste 2 receptor member 63 pseudogene Homo sapiens
2 Phospho-specific Akt (pAkt) and phospho-specific p70 S6 kinase (pS6) were significantly upregulated by nicotine exposure. Nicotine taste 2 receptor member 63 pseudogene Homo sapiens
3 Tumor growth in vivo was significantly induced by nicotine exposure in accordance with increased pS6 expression. Nicotine taste 2 receptor member 63 pseudogene Homo sapiens
4 Nicotine attenuated inhibition of T24 cell growth by CDDP and further upregulated pS6 expression in vitro and in vivo. Nicotine taste 2 receptor member 63 pseudogene Homo sapiens
5 NVP-BZE235 inhibited T24 cell proliferation and pAkt and pS6 expression induced after exposure to nicotine and/or CDDP. Nicotine taste 2 receptor member 63 pseudogene Homo sapiens