Title : Inhibition of Human UDP-Glucuronosyltransferase Enzymes by Canagliflozin and Dapagliflozin: Implications for Drug-Drug Interactions.

Pub. Date : 2015 Oct

PMID : 26180128






1 Functional Relationships(s)
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1 Since the sodium-glucose cotransporter 2 inhibitors share common structural features, notably a glycoside moiety, investigation of drugs in this class for effects on UGT to identify (or exclude) potential drug-drug interactions is warranted. Glycosides solute carrier family 5 member 2 Homo sapiens