Title : Oral administration of the Aureobasidium pullulans-derived β-glucan effectively prevents the development of high fat diet-induced fatty liver in mice.

Pub. Date : 2015 Jul 16

PMID : 26179949






1 Functional Relationships(s)
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1 Liver injury as indicated by an increase in serum alanine aminotransferase (ALT) in the HFD-fed mice was significantly reduced in the mice administered AP-PG orally, and the gene expression of cholesterol 7 alpha-hydroxylase (CYP7A1) which is known to be involved in cholesterol degradation in the liver was significantly increased in the AP-PG administered mice. Cholesterol cytochrome P450, family 7, subfamily a, polypeptide 1 Mus musculus