Title : Isoform-Specific Regulation of Mouse Carboxylesterase Expression and Activity by Prototypical Transcriptional Activators.

Pub. Date : 2015 Dec

PMID : 26179144






1 Functional Relationships(s)
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1 The CAR activator 1,4-bis-[2-(3,5-dichloropyridyloxy)] benzene (TCPOBOP) and PXR ligand pregnenolone-16a-carbonitrile (PCN) increased Ces mRNA expression of various Ces2 isoforms, whereas the Nrf2 activator butylated hydroxyanisole primarily reduced Ces3a mRNA expression and induced Ces1g mRNA. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene carboxylesterase 2H Mus musculus