Title : Methylglyoxal, the foe and friend of glyoxalase and Trx/TrxR systems in HT22 nerve cells.

Pub. Date : 2015 Dec

PMID : 26165190






3 Functional Relationships(s)
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1 We found that nuclear Nrf2 is induced by MGO treatment in HT22 cells, as corroborated by induction of the Nrf2-controlled target genes and proteins glutamate cysteine ligase and heme oxygenase 1. Pyruvaldehyde nuclear factor, erythroid derived 2, like 2 Mus musculus
2 We found that nuclear Nrf2 is induced by MGO treatment in HT22 cells, as corroborated by induction of the Nrf2-controlled target genes and proteins glutamate cysteine ligase and heme oxygenase 1. Pyruvaldehyde nuclear factor, erythroid derived 2, like 2 Mus musculus
3 Nrf2 knockdown prevented MGO-dependent induction of glutamate cysteine ligase and heme oxygenase 1. Pyruvaldehyde nuclear factor, erythroid derived 2, like 2 Mus musculus