Pub. Date : 2015
PMID : 26137220
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BACKGROUND: Pyruvate dehydrogenase (PDH) occupies a central node of intermediary metabolism, converting pyruvate to acetyl-CoA, thus committing carbon derived from glucose to an aerobic fate rather than an anaerobic one. | Carbon | pyruvate dehydrogenase phosphatase catalytic subunit 1 | Homo sapiens |
| 2 | BACKGROUND: Pyruvate dehydrogenase (PDH) occupies a central node of intermediary metabolism, converting pyruvate to acetyl-CoA, thus committing carbon derived from glucose to an aerobic fate rather than an anaerobic one. | Carbon | pyruvate dehydrogenase phosphatase catalytic subunit 1 | Homo sapiens |
| 3 | CONCLUSIONS: Although PDH suppression substantially alters central carbon metabolism, the data indicate that rapid cell proliferation occurs independently of PDH activity. | Carbon | pyruvate dehydrogenase phosphatase catalytic subunit 1 | Homo sapiens |