Title : Advanced squamous lung carcinoma in a patient experiencing long-term survival following repeated responses to gemcitabine and cisplatin chemotherapy: A case report.

Pub. Date : 2015 Jun

PMID : 26137163






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Excision repair cross complementation 1 gene (ERCC1) is involved in the repair of DNA damage caused by cisplatin, and ribonucleotide reductase M1 subunit (RRM1) is associated with gemcitabine resistance in tumor cells. gemcitabine ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens
2 The current study reports the case of a patient with advanced squamous cell lung carcinoma exhibiting low ERCC1 and RRM1 expression levels, who experienced long-term survival following repeated responses to gemcitabine and cisplatin chemotherapy. gemcitabine ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens