Title : Rebamipide Promotes the Regeneration of Aspirin-Induced Small-Intestine Mucosal Injury through Accumulation of β-Catenin.

Pub. Date : 2015

PMID : 26135128






3 Functional Relationships(s)
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Protein Name
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1 Rebamipide Promotes the Regeneration of Aspirin-Induced Small-Intestine Mucosal Injury through Accumulation of beta-Catenin. rebamipide catenin (cadherin associated protein), beta 1 Mus musculus
2 The expressions of COX-2, beta-catenin, and c-myc and the PGE2 concentrations in small intestinal tissues were significantly increased in mice with rebamipide treatments (P < 0.05). rebamipide catenin (cadherin associated protein), beta 1 Mus musculus
3 CONCLUSION: Rebamipide administration in aspirin-induced SII mice could improve the intestinal barrier structure and promote the regeneration of small intestinal epithelial injury through up-regulating COX-2 expression and the accumulation of beta-catenin. rebamipide catenin (cadherin associated protein), beta 1 Mus musculus