Pub. Date : 2015
PMID : 26131136
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | They were intervened by heparin and the expression levels of soluble thrombomodulin (sTM) and serum activated protein C (APC) were detected by ELISA, the regulatory mechanism of heparin improving vascular endothelial cells injury induced by TNFalpha was detected by Western Blotting method, the methylation of histone in the gene promoter region of endothelial nitric oxide synthase (eNOS) and monocyte chemotactic protein-1 (MCP-1) were detected using chromatin immunoprecipitation method. | Heparin | C-C motif chemokine ligand 2 | Homo sapiens |
| 2 | They were intervened by heparin and the expression levels of soluble thrombomodulin (sTM) and serum activated protein C (APC) were detected by ELISA, the regulatory mechanism of heparin improving vascular endothelial cells injury induced by TNFalpha was detected by Western Blotting method, the methylation of histone in the gene promoter region of endothelial nitric oxide synthase (eNOS) and monocyte chemotactic protein-1 (MCP-1) were detected using chromatin immunoprecipitation method. | Heparin | C-C motif chemokine ligand 2 | Homo sapiens |
| 3 | Results Heparin could inhibit the secretion of sTM and APC protein and the expression of MCP-1 gene which involved in NF-kappaB signal pathway. | Heparin | C-C motif chemokine ligand 2 | Homo sapiens |