Title : A Functional and Putative Physiological Role of Calcitriol in Patched1/Smoothened Interaction.

Pub. Date : 2015 Aug 7

PMID : 26126827






4 Functional Relationships(s)
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1 Moreover calcitriol strongly synergizes with itraconazole (ITZ) in Smo inhibition, which did not result from elevated calcitriol bioavailability due to ITZ-mediated 24-hydroxylase inhibition but rather from a direct interaction of the compounds at the level of Smo. Itraconazole smoothened, frizzled class receptor Homo sapiens
2 Moreover calcitriol strongly synergizes with itraconazole (ITZ) in Smo inhibition, which did not result from elevated calcitriol bioavailability due to ITZ-mediated 24-hydroxylase inhibition but rather from a direct interaction of the compounds at the level of Smo. Itraconazole smoothened, frizzled class receptor Homo sapiens
3 Moreover calcitriol strongly synergizes with itraconazole (ITZ) in Smo inhibition, which did not result from elevated calcitriol bioavailability due to ITZ-mediated 24-hydroxylase inhibition but rather from a direct interaction of the compounds at the level of Smo. Itraconazole smoothened, frizzled class receptor Homo sapiens
4 Moreover calcitriol strongly synergizes with itraconazole (ITZ) in Smo inhibition, which did not result from elevated calcitriol bioavailability due to ITZ-mediated 24-hydroxylase inhibition but rather from a direct interaction of the compounds at the level of Smo. Itraconazole smoothened, frizzled class receptor Homo sapiens