Pub. Date : 2015 Jun 26
PMID : 26125901
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We hypothesized that isoflurane induces apoptosis partly by causing excessive calcium release from the endoplasmic reticulum (ER) via direct activation of inositol 1,4,5-trisphosphate receptors (IP3R). | Isoflurane | inositol 1,4,5-trisphosphate receptor, type 1 | Rattus norvegicus |
| 2 | These results suggest that exposure to 1 MAC isoflurane for 12 h causes excessive calcium release partly by direct activation of IP3R on the ER membrane and triggers cell apoptosis. | Isoflurane | inositol 1,4,5-trisphosphate receptor, type 1 | Rattus norvegicus |