Title : Activation of FoxO1/ PGC-1α prevents mitochondrial dysfunction and ameliorates mesangial cell injury in diabetic rats.

Pub. Date : 2015 Sep 15

PMID : 26123583






1 Functional Relationships(s)
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1 In addition, lentiviral-mediated FoxO1 overexpression in diabetic-rat kidneys significantly increased PGC-1alpha, NRF-1, and Mfn2 expression, and decreased malondialdehyde production and proteinuria. Malondialdehyde forkhead box O1 Rattus norvegicus