Title : Apocynin attenuates cholesterol oxidation product-induced programmed cell death by suppressing NF-κB-mediated cell death process in differentiated PC12 cells.

Pub. Date : 2015 Oct

PMID : 26122972

1 Functional Relationships(s)
Compound Name
Protein Name
1 7-Ketocholesterol and 25-hydroxycholesterol decreased the levels of Bid and Bcl-2, increased the levels of Bax and p53, and induced loss of the mitochondrial transmembrane potential, release of cytochrome c and activation of caspases (-8, -9 and -3). 25-hydroxycholesterol Wistar clone pR53P1 p53 pseudogene Rattus norvegicus