Title : Hypusination of eukaryotic initiation factor 5A via cAMP-PKA-ERK1/2 pathway is required for ligand-induced downregulation of LH receptor mRNA expression in the ovary.

Pub. Date : 2015 Sep 15

PMID : 26116232






1 Functional Relationships(s)
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1 Taken together, these results suggest that hCG-induced LHR mRNA downregulation is mediated by cAMP-PKA-ERK1/2 signaling leading to activation of eIF5A hypusination. Cyclic AMP hypertrichosis 2 (generalised, congenital) Homo sapiens