Title : Poly-Electrophilic Sesquiterpene Lactones from Vernonia amygdalina: New Members and Differences in Their Mechanism of Thiol Trapping and in Bioactivity.

Pub. Date : 2015 Jul 24

PMID : 26115003






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Vernolide (1) emerged as a potent inhibitor of STAT3 and NF-kappaB and showed cytostatic activity toward the prostate cancer cell line DU45, arresting the cell cycle at the S phase. vernolide signal transducer and activator of transcription 3 Homo sapiens