Title : DNA methylation directs functional maturation of pancreatic β cells.

Pub. Date : 2015 Jul 1

PMID : 26098213






1 Functional Relationships(s)
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1 Here, we have shown that during postnatal life, the de novo DNA methyltransferase DNMT3A initiates a metabolic program by repressing key genes, thereby enabling the coupling of insulin secretion to glucose levels. Glucose DNA methyltransferase 3 alpha Homo sapiens