Title : APR-246 overcomes resistance to cisplatin and doxorubicin in ovarian cancer cells.

Pub. Date : 2015 Jun 18

PMID : 26086967






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 APR-246 is a prodrug that is converted to the active compound methylene quinuclidinone (MQ), a Michael acceptor that binds to cysteine residues in mutant p53 and restores its wild-type conformation. SCHEMBL4738034 tumor protein p53 Homo sapiens