Title : Contribution of α2A-adrenoceptor subtype to effect of dexmedetomidine and xylazine on spinal synaptic transmission of mice.

Pub. Date : 2015 Aug 15

PMID : 26086861






3 Functional Relationships(s)
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1 Contribution of alpha2A-adrenoceptor subtype to effect of dexmedetomidine and xylazine on spinal synaptic transmission of mice. Dexmedetomidine adrenergic receptor, alpha 2a Mus musculus
2 In alpha2A-AR mutant mice, sVRP suppression by dexmedetomidine was greatly weakened, while that by xylazine (30-100muM) showed only slight attenuation. Dexmedetomidine adrenergic receptor, alpha 2a Mus musculus
3 These results suggest that sVRP suppression by dexmedetomidine and xylazine is mainly mediated by alpha2A-AR. Dexmedetomidine adrenergic receptor, alpha 2a Mus musculus