Pub. Date : 1989 Nov
PMID : 2607315
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Porphobilinogen deaminase concentration (micrograms/gHb) was quantified using a recently developed double-sandwich ELISA. | 4-hydroxybutyric acid | hydroxymethylbilane synthase | Homo sapiens |
| 2 | The majority (91%) of gene carriers, from 25 families, had a diminished porphobilinogen deaminase concentration of 102 +/- 18 micrograms/gHb, with a slightly lowered specific activity of 634 +/- 105 nkat/g. | 4-hydroxybutyric acid | hydroxymethylbilane synthase | Homo sapiens |
| 3 | In 9% of the gene carriers, representing six different families, an increase in porphobilinogen deaminase concentration to 269 +/- 46 micrograms/gHb, and a highly significant reduction in specific activity to 234 +/- 48 nkat/g, were found, which indicates the presence of a different mutation. | 4-hydroxybutyric acid | hydroxymethylbilane synthase | Homo sapiens |