Title : A study of the mechanisms underlying the anti-inflammatory effect of ellagic acid in carrageenan-induced paw edema in rats.

Pub. Date : 2015 May-Jun

PMID : 26069367






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1 RESULTS: The results showed that intraplantar injection of carrageenan led to time-dependent development of peripheral inflammation, which resulted in a significant increase in the levels of tumor necrosis factor alpha (TNF-alpha) and interleukin 1 (IL-1) beta, nitric oxide (NO) and prostaglandin E2 (PGE2) and also iNOS and COX-2 protein expression in inflamed paw. Carrageenan interleukin 1 beta Rattus norvegicus