Title : Simvastatin prevents β-amyloid(25-35)-impaired neurogenesis in hippocampal dentate gyrus through α7nAChR-dependent cascading PI3K-Akt and increasing BDNF via reduction of farnesyl pyrophosphate.

Pub. Date : 2015 Oct

PMID : 26051402






1 Functional Relationships(s)
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1 The results indicate that the SV-treatment in Abeta25-35-mice via reduction of FPP can protect neurogenesis through alpha7nAChR-cascading PI3K-Akt and increasing BDNF, which may improve spatial cognitive function. farnesyl pyrophosphate thymoma viral proto-oncogene 1 Mus musculus