Pub. Date : 2015 Nov
PMID : 26051129
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | All subtypes of prostaglandin E2 (PGE2) receptors (EP1-EP4) were expressed in ileum, and PGE2 and selective EP2 or EP4 agonist inhibited CCh-mediated contraction. | Dinoprostone | prostaglandin E receptor 2 | Rattus norvegicus |
| 2 | In conclusion, LPS induces COX-2 to produce PGE2, which initially activates EP2 and/or EP4 on smooth muscle cells to inhibit the contractility in early phase of LPS exposure. | Dinoprostone | prostaglandin E receptor 2 | Rattus norvegicus |